Cancer Immunotherapy
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The introduction of modern technology has been a boon as well as a bane for people all over the world and of all ages. Smartphones have increased convenience to communicate known people and to stay in touch at all times. But, at the same time, it has only increased health-related problems in people. One such dreadful disease that is being contracted by a huge number of people these days is cancer. Although it is not something new, its spread was very much restricted. But using modern technology has only increased the number of sufferers throughout the world, not only on people but also on birds as well. This has been confirmed by scientists who have been researching to try to identify the side effects of modern technological gadgets. Fortunately, there are readily available treatments for cancer. 

Treating cancer

Recent medical advancements to treat cancer patients have helped with the development of various types of biological therapies which prove to be a wonderful alternative to those age-old practiced cancer therapies. The human body’s immune system is harnessed through Immunotherapy to fight against cancer cells effectively. 

Immunotherapy is said to attack cancer cell growth or stimulate the immune system for destroying the cancer cells. When compared to the standard followed cancer treatment therapies like radiation therapy, chemotherapy that tends to act on both cancerous and normal cells, immune-therapeutic related treatments can be highly specific. There is an available variety of cancer immune-therapy approaches that exist as cancer vaccines, immune checkpoint blockers, monoclonal antibodies, immune-modulators including cell-based immune-therapies. These are stated to have been effective to treat cancer patients. 

Using monoclonal antibodies is considered to be a commonly targeted cancer chemotherapy form since it is customized within the lab setting. They do have unique antigen specificity, thus allowing attachment to particular epitopes on the cancer cells. Cancer cells are flagged and become more visible to the immune system, thereby enabling them to be identified and destroyed. Most monoclonal antibodies presently are undergoing clinical trials associated with phase 3 or waiting for FDA review procedures. Non-specific immune-therapy approaches, unlike that of monoclonal antibodies like immune-modulatory cytokines administration, are used to cure melanoma. Cytokines, produced endogenously by the body are hormones required to suppress or improve T-cell response to fight cancer cells. The commonly characterized cytokines that are used for immune-therapy are IL-2 & IFN-a.

The currently successful main cell-based immune-therapy strategy is actually using T-cell therapy. Here, from blood is removed cancer T cells and modified using CAR chimeric antigen receptor. Then, it gets infused back within the patient to cure metastatic cancer. The other cell-based immune-therapy type is TIL (tumor-infiltrating lymphocytes) therapy, allowing surgical removal of tumor tissue. It is grown in a lab setting by including cytokines and re-infused back within the patient. 

Advanced treatment

The top cancer hospital in India is likely to offer advanced treatment methods to cure different types of cancer. In recent times, a promising treatment for melanoma is considered to be using immune checkpoint inhibitors. Inhibiting checkpoint receptors on the T-cells, they work like brakes on the immune system, thereby mediating anti-tumor responses. CTLA-4, PDL-1, and PD-1 are few common commercialized antibody inhibitors. Vaccine usage to boost the immune system for creating antibodies to target tumor-specific antigens is another focused approach, which helps to eliminate cancerous cells. Some cancer vaccines include dendritic cell-based, peptide-based, DNA cell-based and tumor cell-based. Cancer vaccines are classified as therapeutic or preventative. The latter are available commercial to treat liver and cervical cancer-causing viruses like Hepatitis B virus and human Papillomavirus.

In spite of such medical advancements being made, there are found some limitations to it like unpredictable efficacy, tumor heterogeneity and potential marker identification that still exist within the domain of cancer immune-therapy. Hence, there are currently being researched, tested and developed more targeted cancer prevention strategies and immune therapies. These are expected to deliver the best possible results to treat refractory cancer or relapsed cancer patients. 

Visiting the best cancer treatment in India is likely to provide you with much respite as there will be present the latest technological equipment to identify the type of cancer affected with, location and extent of spread. Accordingly, you can enjoy deriving the best available treatment.

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